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1-2-3 Pressure Down Trio™

1-2-3 Pressure Down Trio™

1-2-3 Pressure Down Trio™ provides targeted natural support for cardiovascular health, formulated by board-certified cardiologist Dr. James Kneller.* This three-part gummy system promotes healthy blood pressure, balanced cholesterol, and improved circulation.*

The bundle includes:
1️⃣ Just Beet It! Gummies with beetroot, grape seed extract, and CoQ10 to enhance nitric oxide production, energize heart cells, and boost circulation and energy. *
2️⃣ Golden Balance Gummies featuring turmeric, ginger, and black pepper to protect cholesterol from oxidation and reduce arterial inflammation for better blood flow.*
3️⃣ Heart Harmony Gummies combining berberine and Ceylon cinnamon to support cholesterol management, insulin sensitivity, and vascular health while providing metabolic support. *
Vegan, gluten-free, non-GMO, and free from bitter aftertaste, these gummies offer a convenient, doctor-formulated approach to long-term heart wellness.*

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FREE E-Book ($97 Value) with every 1-2-3 Pressure Down Trio purchase, “28-Day Natural Blood Pressure Management Protocol,” by Dr. James Kneller.

$90.00 USD
$81.00 USD

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Physician-Designed, Evidence-Based.

This protocol gives you a clear, practical roadmap to reduce blood pressure naturally using safe, sustainable lifestyle strategies and targeted nutritional support.

High blood pressure, high cholesterol, and rising blood sugar aren't three separate problems.

They're one connected cycle.

What we like to call the Vicious Cardiovascular Loop. Each condition fuels the next, quietly exhausting the heart.

  • Just Beet It!™

    Gummies:

    This formula uses therapeutic levels of beetroot, grape-seed extract, and CoQ10 to boost your body’s natural nitric-oxide production. Compared to Super Beets, Just Beet It has – 3 times more beet extract and 6 times more grapeseed extract with an added bonus of CoQ10. Nitric oxide relaxes and opens your arteries, improving blood flow and oxygen delivery throughout your body. The result? More energy, better endurance, and smoother blood pressure — naturally. It’s circulation support you can feel and they taste great, too. In an easy gummy form that requires no water, powders, tinctures – just pop and enjoy!

  • Golden Balance™

    Gummies:

    This formula combines the equivalence of 9000 mg turmeric, ginger, and black pepper — three powerful botanicals that work together to reduce oxidative stress and protect your arteries from cholesterol buildup. I used to encourage my patients to eat turmeric but the amounts therapeutically necessary were almost impossible to swallow. But these gummies taste great and are so convenient – no powdery mess, no chalky aftertaste or bulky capsules. Curcumin soothes inflamed arteries, ginger improves lipid balance, and black pepper amplifies absorption 20-fold. When inflammation cools, arteries stay flexible, and your heart stays young. Those with arthritis or joint pain may see a great side effect of diminished pain as curcumin soothes arteries.

  • Heart Harmony™

    Gummies:

    This formula is a metabolic powerhouse gummy combining berberine and Ceylon cinnamon. Berberine activates your body’s energy regulator — the AMPK pathway — improving how cells use glucose and fat. Cinnamon enhances insulin sensitivity and supports smoother blood flow. Together, they help balance blood sugar, cholesterol, and metabolism — so your heart can finally beat in harmony.

Inside Our Ingredients

Discover the science-backed, natural ingredients that power our products.

Beetroot Powder

Beetroot Powder

Improves blood flow through natural nitrates.

Grape Seed Extract

Grape Seed Extract

Supports heart health with powerful antioxidant protection.

Turmeric

Turmeric

Helps reduce inflammation and supports joint comfort.

Berberine

Berberine

Supports healthy blood sugar and metabolic balance.

Cinnamon

Cinnamon

Helps maintain healthy blood sugar and metabolic function.

CoQ10

CoQ10

Supports heart energy and healthy cellular function.

FAQs

Discover the power in our science-backed, natural ingredient products.

What is included in 1-2-3 Pressure Down Trio™?

This bundle includes three of our physician-formulated cardiovascular support gummies: Just Beet It!™ – High-potency beetroot, grape seed extract, and CoQ10 for nitric-oxide support, circulation, and cellular energy. Golden Balance™ – A turmeric-ginger blend designed to support a healthy inflammatory response and protect cholesterol particles from oxidation. Heart Harmony™ – Berberine + Ceylon cinnamon to support healthy cholesterol, triglycerides, insulin sensitivity, and metabolic function. Each product is vegan, gluten-free, non-GMO, and formulated under clinical guidance.

What does this bundle support?

The bundle is designed by NCI to provide comprehensive cardiovascular wellness through three synergistic pathways: Healthy Blood Pressure Balanced Lipid Levels Improved Circulation & Vascular Function Together, these gummies provide a convenient, natural foundation for long-term heart health support.

How do I take the products?

We recommend taking the gummies daily and consistently. Each product includes its own serving instructions on the bottle. For best results, we advise 3–6 months of continuous use so your cardiovascular markers have time to respond.

How long until I may see benefits?

Some customers report feeling improvements—such as better energy or healthier blood-pressure patterns—within 4–6 weeks. For measurable changes in cholesterol or blood-pressure labs, most individuals see optimal results between 3–6 months of consistent use.

 Are the ingredients scientifically supported?

Yes. Each formula uses clinically researched plant compounds known to support heart health. Examples include: Beetroot for nitric oxide and vessel relaxation Grape seed extract for antioxidant vascular protection CoQ10 for mitochondrial and cardiac energy Turmeric, ginger, and black pepper for anti-inflammatory and lipid-supporting benefits Berberine and Ceylon cinnamon for metabolic and cholesterol balance We formulate with therapeutic equivalencies (20:1, 30:1 extracts, etc.) to deliver meaningful, therapeutic potency in a gummy format.*

Can this bundle replace prescription medications?

No. Our products are dietary supplements and are not intended to replace physician-prescribed medications. Many customers use the bundle alongside their traditional care—always with their doctor’s knowledge and supervision.

Is the bundle safe to use with other supplements or medications?

Our formulas are generally well-tolerated, but because they influence cardiovascular and metabolic pathways, individuals taking: blood-pressure medications blood-thinners diabetes medications statins should consult their healthcare provider before beginning supplementation.

Who formulated these products?

All NCI formulations are developed under the guidance of Dr. James Kneller, a board-certified cardiologist and electrophysiologist. They reflect more than 20 years of clinical experience in both traditional and integrative cardiology.

Are your products manufactured in the United States?

Yes. All NCI supplements are produced in the USA in a GMP-certified facility, following strict quality, purity, and potency standards.

Are the gummies vegan and allergen-friendly?

Yes. The entire bundle is: 100% vegan Gluten-free Non-GMO Free of artificial colors or preservatives We design our formulas to be clean, natural, and easy to incorporate into daily life.

Do the gummies contain sugar?

We use low-sugar formulations with natural sweeteners to ensure the products are effective, enjoyable, and suitable for most heart-healthy lifestyles.

Do you offer subscriptions?

Yes. NCI offers subscription options for customers who want uninterrupted access to their heart-health regimen. Subscribers receive: Exclusive discounts Access to educational webinars and Q&A sessions Early access to new products You may pause, modify, or cancel your subscription at any time.

Are these products safe for long-term use?

When used as directed, our formulations are designed for daily, long-term cardiovascular support. Many ingredients—such as beetroot, turmeric, and berberine—have been used safely for thousands of years. However, ongoing communication with your healthcare provider is always recommended.

What if I am pregnant or breastfeeding?

Please consult your healthcare provider before using any NCI supplement during pregnancy or while breastfeeding.